Mastering the art of patient‑focused treatment
Pipeline/Trials
Our commitment to excellence
Taking on the challenges inherent in today’s cancer treatments isn’t easy…but we’re up for it. We are Athenex—a team of scientists, investigators, and innovators driven by the patients we serve. Our robust investigational pipeline of novel small molecule, biologic, and cellular therapies is focused on both improving outcomes and improving the cancer treatment experience for patients around the world.
Program
Drug candidate
Indication
Pre-clinical
Phase 1
Phase 2
Phase 3
Angiosarcoma
Oral paclitaxel + encequidar with dostarlimab**
Neoadjuvant breast cancer
(I-SPY 2)
Oral topotecan + encequidar
Solid tumors
Oral eribulin + encequidar
Solid tumors
Src Kinase Inhibition
Tirbanibulin ointment
Actinic keratosis
TCR-T Immunotherapy
TCRT-ESO-A2
Multiple tumors
Arginase Deprivation Therapy
PT01
Multiple tumors
Posted pipeline was current on March 1, 2021. Pipeline may not reflect changes in phase of development after March 1, 2021.
* Encequidar is the international nonproprietary name (INN) for HM30181A, our novel P-gp pump inhibitor molecule.
** Collaboration with Quantum Leap Healthcare Collaborative and GlaxoSmithKline.
*** Collaboration with Eli Lilly and Company, makers of ramucirumab.
Clinical Platform
Orascovery
(RECEIVED CRL FROM FDA)
Angiosarcoma
Oral paclitaxel + encequidar with dostarlimab**
Neoadjuvant breast cancer
(I-SPY 2)
Oral topotecan + encequidar
Solid tumors
Oral eribulin + encequidar
Solid tumors
Clinical Platform
Src Kinase Inhibition
Tirbanibulin ointment
Actinic keratosis
(FDA APPROVED)
Clinical Platform
TCR-T Immunotherapy
TCRT-ESO-A2
Multiple tumors
Clinical Platform
Arginase Deprivation Therapy
PT01
Multiple tumors
Posted pipeline was current on March 1, 2021. Pipeline may not reflect changes in phase of development after March 1, 2021.
* Encequidar is the international nonproprietary name (INN) for HM30181A, our novel P-gp pump inhibitor molecule.
** Collaboration with Quantum Leap Healthcare Collaborative and GlaxoSmithKline.
*** Collaboration with Eli Lilly and Company, makers of ramucirumab.